Phase 1 study

Recruiting Phase 1

Sources: ClinicalTrials.gov Checked: 11 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 1
Sponsor Third Arc Bio
Registry number NCT06672185
Started 5 February 2025 Today 16 October 2026 Estimated completion 1 May 2028

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Sunshine Coast University Private Hospital Birtinya QLD Recruiting
Cancer Research SA Adelaide SA Recruiting
Cabrini Health Research Malvern VIC Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice

Who can join

Age 18 Years and over
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 70

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* Locally advanced or metastatic solid tumor ovarian, testicular or other Claudin 6+ cancers

* Measurable or evaluable disease, per RECIST v1.1

* Eastern Cooperative Oncology Group (ECOG) performance status 0-1

* Adequate organ function

Exclusion Criteria:

* Active CNS involvement

* Malignancy diagnosis other than the disease under study within 2 years prior to the first dose of study drug.

* Presence of uncontrolled ascites

* Toxicity related to prior anticancer therapy that has not returned to Grade ≤1 or baseline levels

* Clinically significant pulmonary compromise

* Active autoimmune disease within 12 months prior to first dose of study drug.

* Female participant who is pregnant, breastfeeding, or plans to become pregnant or male participant who plans to father a child either while enrolled or within 90 days after the final administration of study drug.

Dates on the record

Started 5 February 2025
Estimated completion 1 May 2028
Registry last updated 27 August 2026
Checked by Voxsanity 11 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 27 August 2026.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.