Kidney Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 80 at the time of signing the consent form, of any gender, who are well enough to carry out daily activities with little or no limitation (as measured by a standard performance score of 0 or 1)
• People who have been diagnosed with kidney cancer that contains clear cell components, confirmed by a tissue or cell sample, including cases where the cancer has spread or come back and cannot be removed by surgery
• People whose cancer has at least one measurable area that can be tracked using standard imaging guidelines (RECIST version 1.1)
• People whose major organs (such as heart, liver, and kidneys) are functioning well enough to meet the trial's requirements
• People who have read, understood, and voluntarily signed the trial's consent form

Who may not be able to join:

• People who have had another type of cancer in the past 5 years, unless it was a type considered fully treatable (such as certain thyroid cancers, cervical carcinoma in situ, certain skin cancers, or breast ductal carcinoma in situ treated with surgery)
• People who have received other cancer treatments — including targeted therapy, immunotherapy, local treatments, or other experimental treatments — within 4 weeks before the trial starts (confirm with trial site regarding the 5 half-lives rule for certain medications)
• People who have had a major surgical procedure within 4 weeks before the trial starts, or who are still recovering from one
• People with a history of severe allergic reactions to drugs, including antibody-based medicines
• People who have medical reasons preventing them from restarting immunotherapy
• People who have previously received a donated organ or stem cell transplant, particularly if long-term steroid use would be needed as a result (some hormone-related conditions that are well-controlled may still be eligible — confirm with trial site)
• People who still have significant side effects from previous cancer treatments that have not returned to near-normal levels (with some exceptions, such as permanent but stable conditions like hearing loss, or hair loss)
• People who have cancer that has spread to the brain or the lining around the brain or spinal cord
• People with a known history of significant liver disease, including active viral hepatitis
• People with uncontrolled fluid build-up in body cavities (such as around the lungs, in the abdomen, or around the heart) that requires repeated draining (some stable cases may still be eligible — confirm with trial site)
• People with any severe or uncontrolled medical condition
• People whose kidneys have failed to the point of requiring dialysis
• People who have, or are suspected to have, an active autoimmune disease (such as lupus, rheumatoid arthritis, or inflammatory bowel disease)
• People who have received a live vaccine within 4 weeks before the trial starts, or who would need one during the trial
• People with a history of misusing mind-altering substances and who are unable to stop, or people with a history of serious mental health disorders
• People with other serious medical or psychiatric conditions, or significant abnormal lab results, that the trial doctors believe could put them at risk or affect the trial's results

Important: Always verify eligibility with the trial site directly before applying.