Leukaemia Trial, Recruiting NCT06684964 Sponsor: Novartis Pharmaceuticals Condition: Leukaemia
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Leukaemia Trial, Recruiting

NCT06684964
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have signed and dated a consent form agreeing to take part in the study
  • People aged 18 or older who have been diagnosed with Philadelphia chromosome-positive chronic myeloid leukaemia in the chronic phase (a specific type of blood cancer at an early stage)
  • People whose blood and bone marrow test results fall within specific ranges — less than 15% blast cells, less than 30% blasts plus promyelocytes, less than 20% basophils, and a platelet count of at least 50,000 per mm³ (confirm with trial site if these terms are unfamiliar)
  • People who have previously been treated with at least 2 different targeted therapy drugs known as TKIs, including imatinib, and at least one of dasatinib, nilotinib, bosutinib, or ponatinib
  • People who are already receiving a drug called asciminib as part of their current treatment, in line with its approved use in their country, and who started asciminib no more than 6 months before joining the study

Who may not be able to join:

  • People for whom asciminib was the first or second treatment tried for their condition
  • People who are currently taking part in another clinical trial
  • People who have declined to sign the informed consent form
  • People who, in the treating doctor's judgement, are unlikely to be able to provide an accurate medical history or to be followed up over the long term — for example, due to serious other illnesses or availability concerns

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Phone: +41613241111

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 March 2025
Est. completion
30 December 2026

Where this trial is recruiting

🇸🇦 Saudi Arabia

Primary endpoints

Major molecular response (MMR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov