Endometrial Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 50 years old
• People who are pre-menopausal or in the early stages of menopause, with a hormone level (FSH) below 25 mIU/ml
• People with a body mass index (BMI) under 33, or where the tissue layer of the abdominal wall measures less than 5 cm
• People whose uterus is no larger than the size typically seen at 18 weeks of pregnancy, based on a physical examination
• People who have a fibroid (a non-cancerous growth in the uterus) that sits within the uterine wall, measures between 3 cm and 10 cm, and is the largest one present on imaging
• People whose fibroids are causing symptoms such as heavy periods, a feeling of pressure, or pelvic pain
• People who are willing and able to give their informed consent to participate

Who may not be able to join:

• People who have another growth or condition in the pelvic area, such as endometriosis, an abnormal mass on the ovaries, an ovarian tumour, or pelvic inflammatory disease (either current or ongoing)
• People with severe obesity
• People who are unable to lie face-down for more than 2 hours
• People who have significant scarring on the abdomen in the area where sound waves would need to pass through during treatment
• People who are pregnant, breastfeeding, or have gone through menopause
• People where a pre-cancerous or cancerous condition of the uterus cannot be confidently ruled out through clinical assessment and MRI
• People whose fibroids have grown very rapidly, meaning they doubled in size within 6 months
• People who have had, or currently have, a blood clot condition such as deep vein thrombosis, a pulmonary embolus (clot in the lungs), or a stroke
• People who have a blood clotting disorder or who take medication that affects how their blood clots
• People who have previously had radiation treatment to the pelvic area
• People with a specific type of fibroid (called pedunculated) that hangs from a narrow stalk, measures 5 cm or larger, and where the stalk is less than 25% of the fibroid's width
• People with fibroids located in or around the cervix or broad ligament area of the uterus
• People who are unable to have an MRI scan, due to severe claustrophobia or having a metal implant in their body
• People who also have adenomyosis (a condition where the uterine lining grows into the uterine wall)

Important: Always verify eligibility with the trial site directly before applying.