Phase 1 Muscular Dystrophy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with Duchenne muscular dystrophy (DMD), confirmed by a genetic test showing a mutation in the DMD gene and/or a muscle biopsy showing no dystrophin protein
• You are not able to walk (non-ambulatory)
• You have a specific small muscle in both feet (called the extensor digitorum brevis) that is still working (confirm with trial site)
• You have not taken any experimental treatments for more than 30 days before joining
• You are 18 years old or older at the time of signing consent
• Your organs (such as kidneys, liver, heart, and lungs) are working well enough, confirmed by blood and other tests done within a recent timeframe before enrolling
• If you have a partner who could become pregnant, you must be willing to use at least two forms of birth control (one must be a barrier method, such as a condom) during the study and for 3 months after stopping one of the study medications (tacrolimus)
• You are able to understand and follow instructions well enough to complete the required tasks during the study
• You are willing to be monitored for up to 15 years, as required for studies involving genetically modified cells
• You are willing to give your written consent to participate in the study voluntarily

Who may not be able to join:

• You have certain antibodies in your blood that react against the transplant product used in this trial (called MyoPAXon) (confirm with trial site)
• You are currently receiving another experimental treatment
• You have a known allergy to any ingredients in MyoPAXon

Important: Always verify eligibility with the trial site directly before applying.