Phase 2 Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with non-small cell lung cancer (NSCLC) confirmed by a tissue test
• People whose cancer is at stage Ib, IIa, IIb, or IIIa (N2), as classified by standard staging guidelines
• People aged 18 or older who are considered medically suitable for lung cancer surgery
• People who have not previously received chemotherapy or radiation therapy to the chest area
• People with normal liver and kidney function at the time of joining the study
• People whose blood test results meet specific thresholds for white blood cells, infection-fighting cells (neutrophils), red blood cells (haemoglobin), platelets, liver enzymes, bilirubin, creatinine, kidney function (eGFR), and blood clotting levels (confirm with trial site for exact values)
• People whose heart rhythm measurement (specifically the QT interval) falls within acceptable ranges — below 450 milliseconds for men and below 470 milliseconds for women
• People whose surgeon has determined that complete surgical removal of the lung cancer and nearby lymph nodes is possible (wedge resection, segmentectomy, or lobectomy are all acceptable)
• People who are willing and able to follow all study procedures for the full duration of the trial
• People who are able to understand and sign an informed consent form
• Women who could become pregnant must use a highly effective form of contraception for at least 6 months after the study treatment is inserted — or must be post-menopausal (confirmed by specific hormone levels) or surgically sterile; men must use highly effective contraception for at least 3 months after treatment insertion (acceptable methods include hormonal contraceptives, intrauterine devices, surgical sterilisation, vasectomy, or consistent abstinence — calendar or symptom-based methods are not accepted)

Who may not be able to join:

• People whose cancer has grown extensively into surrounding structures (T3 or T4) or has spread to other parts of the body
• People who would need a full lung removal (pneumonectomy) or a sleeve resection procedure
• People with a known allergy or sensitivity to any component of the study treatment
• People who have had another cancer within the past 5 years, except for certain common skin cancers (non-melanoma skin cancer)
• People who have already received chemotherapy or radiation therapy before surgery as part of their current treatment
• People with serious uncontrolled health conditions, such as active infection, major organ problems (liver, kidney, etc.), poorly controlled heart failure, unstable chest pain, irregular heart rhythms, or significant mental health or social circumstances that could affect participation
• People who are currently pregnant or breastfeeding
• People who are unwilling or unable to follow the study's requirements
• People with any other condition that, in the investigator's judgement, could interfere with their ability to participate safely and consistently in the trial

Important: Always verify eligibility with the trial site directly before applying.