Phase 3 Tuberculosis Trial, Recruiting NCT06727864 Sponsor: Kaohsiung Veterans General Hospital. Condition: Tuberculosis
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Phase 3 Tuberculosis Trial, Recruiting

NCT06727864
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have recently been diagnosed with tuberculosis (TB) in your lungs, confirmed by a lab test, tissue sample, or a doctor's clinical assessment
  • You had TB in the past but were fully cured at least 3 years ago
  • You are 21 years old or older
  • Your recent blood tests (taken within the last 14 days) show that your liver, kidneys, blood cell counts, and platelets are within acceptable ranges (confirm with trial site for specific values)
  • You are willing to sign a consent form agreeing to take part in the study
  • You agree to follow the local health authority's treatment plan to make sure you take your medications as directed

Who may not be able to join:

  • Your sputum (mucus/phlegm) test shows a very high level of TB bacteria (described as "strongly positive")
  • Your chest X-ray or CT scan shows open or cavity-type areas of infection in your lungs
  • Your chest X-ray or CT scan shows very widespread disease and your doctor feels a shorter treatment course would not be appropriate
  • You have TB both inside and outside of your lungs at the same time
  • You are unable to swallow or take oral (by mouth) medications
  • You have already taken part in this study before
  • You have already been taking TB medications for more than 14 days
  • You have a history of TB affecting the brain or nervous system, bones or joints, widespread TB throughout the body (miliary TB), or TB around the heart
  • You have a known allergy or bad reaction to the study medication
  • You have HIV infection, have had an organ transplant, or have chronic kidney failure
  • You have been taking immune-suppressing medications (including steroids above a certain dose) for a long period recently
  • During the study, if it is found that your TB bacteria are resistant to key TB medications (rifampin, isoniazid, or ethambutol), you may be removed from the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Susan Shin-Jung Lee, MD, PhD, Kaohsiung Veterans General Hospital.

Phone: +886-7342-2121

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Kaohsiung Veterans General Hospital.
Registry
ClinicalTrials.gov
Start date
1 January 2024
Est. completion
31 December 2027

Where this trial is recruiting

🇹🇼 Taiwan

Primary endpoints

TB disease free survival at 12 months post-randomization; TB disease free survival at 24 months post randomization; Grade 3-5 adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov