Osteoporosis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women who have gone through menopause and are between 60 and 90 years old
• People whose bone density scan results show bones that are weak enough to be considered osteoporosis (a T-score below -2.5 at the spine or hip), but not lower than -4.0 at either site
• People who either meet the government health insurance (NHI) criteria for a specific bone-strengthening medication (denosumab), or who do not meet those criteria or do not wish to receive that medication during the study (two separate groups in the trial)
• People who have never been treated for osteoporosis before, or who took a type of bone medication called bisphosphonates for less than 3 years and not within the last 12 months
• People who have at least 2 assessable vertebrae in the lower spine and at least one assessable hip that can be measured by bone density scanning
• People who are willing to limit extra Vitamin D3 supplements to no more than 400 or 800 IU per day during the study
• People who are able to follow all study instructions and complete all required visits and procedures
• People who are willing to sign a written consent form agreeing to participate

Who may not be able to join:

• People who have conditions that affect bone health, such as Paget's disease or osteomalacia (soft bones)
• People who have taken certain bone or hormone-related medications within the 6 weeks before the screening visit, including parathyroid hormone treatments, corticosteroids (steroids), hormone replacement therapy, certain estrogen-related drugs, calcitonin, or calcitriol
• People whose blood test shows a Vitamin D level below 12 ng/ml
• People whose bone density T-score is lower than -4.0 at the spine or hip
• People who have a severe spinal fracture, or more than two moderate spinal fractures, found on an X-ray at the time of screening
• People who plan to start a new bisphosphonate (a type of bone medication) during the study
• People who have a known allergy or sensitivity to any ingredient in the study medication
• People who have taken part in another clinical trial within the 30 days before starting study medication
• People whose overall health, in the treating doctor's judgement, could affect the safety or accuracy of the trial results

Important: Always verify eligibility with the trial site directly before applying.