Myasthenia Gravis Trial, Recruiting NCT06743490 Sponsor: Leiden University Medical Center Condition: Myasthenia Gravis
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Myasthenia Gravis Trial, Recruiting

NCT06743490
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older
  • You are able to understand what the study involves and are willing to sign a consent form

If you have Myasthenia Gravis (MG):

  • You have been formally diagnosed with myasthenia gravis (either affecting only the eyes, or more widespread), classified as "definite" or "probable" according to Dutch national guidelines
  • Your MG severity falls within a certain range on a standard medical scale (levels I through IV) (confirm with trial site)
  • You currently experience at least one of these symptoms: slurred speech, changes to your voice, weakness in your upper arms, and/or drooping eyelids

If you do not have Myasthenia Gravis:

  • You have not been diagnosed with MG and there is no medical reason to suspect you have it
  • You have no history of slurred speech, voice changes, upper arm weakness, or drooping eyelids

Who may not be able to join:

  • You are not willing to have your voice recorded during the study
  • You are not willing to be filmed during the study
  • You are currently taking part in another clinical trial involving an experimental medicine
  • You have taken a short-acting pyridostigmine-based medication in the 12 hours before taking part, or you currently take a long-acting version of this medication
  • You have cognitive or physical difficulties that would prevent you from completing the study tasks, in the opinion of the study doctor

If you have Myasthenia Gravis:

  • You have had an arm amputated or are unable to speak
  • You have another diagnosed neurological condition (separate from MG) that causes muscle weakness

If you do not have Myasthenia Gravis:

  • You have any condition that limits the movement of your arms or affects your ability to speak

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Martijn R. Tannemaat, MD, PhD, Leiden University Medical Center

Phone: +31715262197

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Leiden University Medical Center
Registry
ClinicalTrials.gov
Start date
18 March 2025
Est. completion
28 August 2026

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Differentiating between MG-patients and non-MG participants using digital features of dysarhtria, dysphonia, proximal arm fatigue and ptosis.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov