Phase 3 Rheumatoid Arthritis Trial, Recruiting NCT06747949 Sponsor: Amgen Condition: Rheumatoid Arthritis
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Phase 3 Rheumatoid Arthritis Trial, Recruiting

NCT06747949
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who gave their informed consent before any study activities began
  • People who previously took part in one of the related Phase 3 Sjögren's syndrome studies (HZNP-DAZ-301 or HZNP-DAZ-303), received the study drug or placebo, and completed that study up to the Week 48 point
  • People who are able to receive the first dose of this follow-on study within 28 days of their Week 48 visit in the previous study

Who may not be able to join:

  • People who have a significant active infection on Day 1, including ongoing or long-term infections that need antibiotic or antiviral treatment, as assessed by the study doctor
  • People who plan to take part in another clinical trial involving an investigational drug or procedure during this study
  • People whose health changed or worsened during the earlier Phase 3 studies in a way that, in the opinion of the study doctor or sponsor, could affect safety assessments or change the risks of taking the study drug
  • People who have planned surgeries or hospital stays that, in the opinion of the study doctor or sponsor, could interfere with safely monitoring and evaluating the study
  • People who plan to receive a live or live-attenuated vaccine during this study
  • Women who are able to become pregnant but are unwilling to use the contraception method specified in the study plan during treatment and for 12 weeks after the last dose
  • Women who are pregnant, breastfeeding, or planning to become pregnant during the study
  • People who have a known allergy or sensitivity to any of the study drug ingredients or related products
  • People who are unlikely to be able to attend all required study visits or follow all required study procedures, to the best of the participant's and study doctor's knowledge
  • People who have a history of, or currently have, any other significant health condition that, in the opinion of the study doctor or an Amgen physician, could pose a safety risk or affect how the study results are evaluated

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: MD, Amgen

Phone: 866-572-6436

Australian sites

The Queen Elizabeth Hospital, Woodville South, South Australia

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
25 February 2025
Est. completion
11 December 2029

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇧🇪 Belgium 🇧🇷 Brazil 🇨🇦 Canada 🇨🇱 Chile 🇭🇷 Croatia 🇫🇷 France 🇩🇪 Germany 🇬🇷 Greece 🇭🇺 Hungary 🇮🇱 Israel 🇮🇹 Italy 🇯🇵 Japan 🇲🇽 Mexico 🇳🇿 New Zealand 🇵🇪 Peru 🇵🇱 Poland 🇵🇹 Portugal 🇷🇸 Serbia 🇸🇮 Slovenia 🇰🇷 South Korea 🇪🇸 Spain 🇹🇼 Taiwan 🇬🇧 United Kingdom 🇺🇸 United States

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Number of Participants with Treatment-emergent Adverse Events (TEAEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov