Non-Alcoholic Fatty Liver Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Part A:
- Male volunteers aged 18 to 70 years old
- Either non-obese (with a body mass index — a measure of body weight relative to height — below 30) or obese (with a body mass index above 30)
Part B:
- Male volunteers aged 18 to 70 years old
- People with a liver fat content between 6.2% and 16.5%, which corresponds to a moderate level of fat in the liver (confirm with trial site)
Who may not be able to join:
Both Parts A and B:
- People with diabetes, including those with high fasting blood sugar levels, high blood sugar after a specific glucose test, or those currently taking diabetes medication
- People with other serious illnesses, such as heart or blood vessel disease, or cancer
- People who drink more than 30 grams of alcohol per day (roughly two to three standard drinks)
- People who take medications that affect how the body processes fats
Part A only:
- People with fructose intolerance (an inability to properly process a type of sugar found in fruit and some foods)
Part B only:
- People who are unable to undergo an MRI scan, for example due to claustrophobia (fear of enclosed spaces) or having certain metal implants in their body
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Dita Pajuelo, PhD, Institute for Clinical and Experimental Medicine
Phone: 00420236053369
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
The comparison of the increment of hepatic fat content after high-fat load to repeated doses of glucose, fructose, and sucrose; The comparison of the increment of HFC after high-fat load with repeated doses of simple sugar between non-obese and obese-subjects; The comparison of hepatic fat content values after short-term (7 days) restriction of fructose from the diet in subjects with fatty liver; Change of hepatic fatty acid profile after short-term restriction of fructose; Change of fatty acid profile of triglycerides in very low-density lipoproteins after short-term restriction of fructose;...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.