Phase 2 Cystic Fibrosis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 75 years old (inclusive), either male or female
• If you are female, you weigh at least 45 kg (about 99 lbs); if you are male, you weigh at least 50 kg (about 110 lbs)
• A special lung scan (HRCT) has shown bronchiectasis (widening/damage of the airways) in one or more parts of your lungs, and a doctor has confirmed this is not related to cystic fibrosis
• You are expected to live for more than 12 months
• You are willing and able to sign a consent form before the trial begins
• If you are able to have children, you are willing to use appropriate contraception during the trial

Who may not be able to join:

• You have been diagnosed with pulmonary hypertension (high blood pressure in the lungs), COPD, or asthma as your main lung condition
• You currently have an active respiratory virus infection, such as COVID-19 or flu, with symptoms
• You have psoriasis or lichen planus (certain skin conditions)
• You have certain skin or joint conditions including Wright's disease, keratosis, hemorrhagic keratosis, or reactive arthritis (confirm with trial site)
• You have chlorine acne, large common warts, or keratodermatitis (certain skin conditions) (confirm with trial site)
• You have a diabetic foot condition
• You have gum disease, an oral infection, or loose teeth
• You have had a cancer diagnosis within the past 5 years
• You have a history of liver disease or are currently being treated for liver problems, including hepatitis, cirrhosis, or liver failure
• You have any other unstable medical condition, as judged by the trial doctors
• You have taken oral or inhaled antibiotics in the 4 weeks before starting the trial
• You have taken immune-suppressing medications in the 4 weeks before starting the trial
• You have taken any medications that may cause skin thickening in the 4 weeks before screening (confirm with trial site)
• You have received a live vaccine (such as certain flu or travel vaccines) within 30 days before starting the trial
• You have taken part in a medical device clinical trial within the past 3 months
• You have an active hepatitis B or C infection, HIV, or syphilis
• You currently misuse drugs
• You are a current smoker, or you stopped smoking less than 3 months ago
• You are known or suspected to be allergic to the trial drug or any of its ingredients, or you have had a severe allergic reaction to any drug, food, or other substance
• You are pregnant or breastfeeding
• You are unable to complete questionnaires or forms yourself, and neither you nor a family member is able to fill in a study log (confirm with trial site)
• The trial doctors decide there is any other reason that makes participation unsuitable for you

Important: Always verify eligibility with the trial site directly before applying.