Phase 2 Chronic Kidney Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
For Patients with Chronic Kidney Disease (CKD):
Who might be able to join this trial:
- People aged 18 or older
- People who have been diagnosed with chronic kidney disease (CKD) of any cause, with kidney function and protein-in-urine levels within specific ranges at screening (confirm with trial site)
- People who have been on a stable blood pressure medication routine for at least 2 weeks before the trial starts and can continue that routine throughout the study
- People whose blood pressure at the screening visit falls within a specific range — not too high and not too low (confirm with trial site)
- People who are able to understand and sign a consent form and follow the study requirements
- Women who could become pregnant must have a negative pregnancy test at the screening visit and must use contraception during the study and for one week after the study treatment ends
Who may not be able to join:
- People currently taking certain medications including Amiloride, Spironolactone, or Aldosterone (or similar drugs)
- People currently taking anti-inflammatory painkillers known as NSAIDs (such as ibuprofen)
- People with high potassium levels in their blood at screening
- People with elevated bilirubin (a liver-related substance) in their blood at screening
- People currently undergoing cancer treatment
- People who have received immune-suppressing medications within the 6 months before screening
- People who have had an organ transplant at any point
- People showing signs of an active infection at the time of screening
- People with severe liver disease (classified as Child-Pugh C)
- People who are currently breastfeeding
- People with severe or unstable heart failure
- People who have had certain heart or cardiovascular events — such as a heart procedure, stroke, mini-stroke, or acute heart condition — within the 2 months before screening
- People with a known allergy or sensitivity to the study medication
- People with Addison's disease (a condition affecting the adrenal glands)
- People who have had gastric bypass surgery
- People with lactose intolerance, as the study medication contains lactose
- People who have participated in another clinical trial within the last 30 days
For Healthy Volunteers:
Who might be able to join this trial:
- People aged 18 or older
- People in good general health with no significant medical conditions or chronic illnesses (such as diabetes, high blood pressure, heart disease, autoimmune diseases, or cancer)
- People with normal kidney function and no protein detected in their urine at screening
- People whose blood pressure at screening is below a specific threshold (confirm with trial site)
- People who are able to understand and sign a consent form and follow the study requirements
- Women who could become pregnant must have a negative pregnancy test at the screening visit and must use contraception during the study and for one week after the study treatment ends
Who may not be able to join:
- People taking any prescription medication, with the exception of oral contraceptives
- People currently taking anti-inflammatory painkillers known as NSAIDs (such as ibuprofen)
- People with high potassium levels in their blood at screening
- People with elevated bilirubin (a liver-related substance) in their blood at screening
- People showing signs of an active infection at the time of screening
- People who are currently breastfeeding
- People with a history of substance abuse, including alcohol
- People with a known allergy or sensitivity to the study medication
- People who have had gastric bypass surgery
- People with lactose intolerance, as the study medication contains lactose
- People who have participated in another clinical trial within the last 30 days
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Claus Bistrup, MD, Professor, Department of Nephrology, Odense University Hospital, Denmark
Phone: +4523368077
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
24 h Urine sodium excretion (mmol/day); Water excretion (L); Total Body Water (L); Home blood pressure
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.