Cystic Fibrosis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
'Mama' sub-study (for people with CF who are pregnant or planning pregnancy):
- A person who is willing and able to give written agreement to take part in the study
- A person who is already a patient at the Royal Brompton Hospital CF Reproductive and Maternal Health Service
- A person who is 16 years of age or older at the time of joining the study
- A person who has a confirmed diagnosis of cystic fibrosis (CF)
- A person who is either pregnant or planning to become pregnant at the time of joining the study
- A person who is able to attend the required appointments and complete the required tests
'Mini' sub-study (for babies with a parent who has CF):
- A baby whose parent or guardian is willing and able to give written agreement for the baby to take part
- A baby who has at least one biological parent with a confirmed CF diagnosis, where that parent is a patient at the Royal Brompton Hospital Adult CF Service
- A baby who is under 12 months old at the time of the first visit
- A baby whose family is able to attend the required appointments and complete the required tests
'Midi' sub-study (for young children with a parent who has CF):
- A child whose parent or guardian is willing and able to give written agreement for the child to take part
- A child who has at least one biological parent with a confirmed CF diagnosis, where that parent is a patient at the Royal Brompton Hospital Adult CF Service
- A child who is between three and six years old at the time of the visit
- A child whose family is able to attend the required appointments and complete the required tests
Who may not be able to join:
'Mama' sub-study:
- A person who has a significant health condition that the study doctor believes would prevent them from safely following the study requirements
- A person who has previously had a lung transplant
'Mini' sub-study:
- A baby whose parent or guardian is not able to give consent for the baby to take part
- A baby whose mother has significant health conditions unrelated to CF that the study doctor believes could affect the baby's health outcomes
'Midi' sub-study:
- A child whose parent or guardian is not able to give consent for the child to take part
- A child who has a significant health condition that the study doctor believes is known to affect lung function or lung imaging results
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Imogen Felton, Royal Brompton Hospital and NHLI Imperial College London
Phone: 020 7352 8121
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in FEV1; Incidence of CF-related pulmonary complications during pregnancy.; Incidence of premature delivery; Frequency of liver dysfunction in infants; Incidence of congential abnormalities; Frequency of CF diagnoses in infants despite negative newborn screen testing; Frequency of abnormal lung clearance index results in young children
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.