Early Phase 1 Brain Cancer Trial, Recruiting NCT06810336 Sponsor: University of Virginia Condition: Brain Cancer
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Early Phase 1 Brain Cancer Trial, Recruiting

NCT06810336
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 65 years old
  • You are scheduled to have brain surgery on the upper part of the brain (called supratentorial surgery)
  • Your overall health has been rated as acceptable for surgery by your anesthesia team (ASA status I, II, or III — confirm with trial site if unsure what this means)
  • Your body weight falls within a healthy to moderately obese range (BMI between 18.5 and 45)
  • You are able to read and understand English

Who may not be able to join:

  • You are unable or unwilling to sign a consent form
  • You are expected to be discharged from the hospital within 24 hours after surgery
  • You need emergency surgery
  • You currently use the pain medication methadone, or you are allergic to it
  • You have ongoing chronic pain that requires you to take opioid pain medications every day, at a level the FDA considers "opioid tolerant," or you use long-acting opioids such as fentanyl patches or extended-release oxycodone
  • You have a current or past substance use disorder, or you are being treated with medications for opioid use disorder such as methadone, buprenorphine (any form), or naltrexone
  • You have significant kidney problems before surgery (confirm with trial site for specific lab values)
  • You are pregnant
  • You have serious liver disease, such as cirrhosis or liver failure
  • A pre-surgery heart test (ECG) shows a specific abnormality in your heart's electrical activity (QTc greater than 450 — confirm with trial site if unsure)
  • You require oxygen at home due to a lung condition
  • You are unable to speak or read English

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Phone: 434-297-8136

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
10 March 2025
Est. completion
10 September 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Quality of recovery after surgery on postoperative day 1,2,3 using QoR-15 psychometrical questionnaire (range 0-150).

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov