Phase 1 Leukaemia Trial, Recruiting NCT06810583 Sponsor: St. Jude Children's Research Hospital Condition: Leukaemia
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Phase 1 Leukaemia Trial, Recruiting

NCT06810583
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 25 years or younger at the time of joining the trial
  • People being treated for AML (a type of blood cancer) or relapsed ALL (a type of blood cancer that has come back) at St. Jude Children's Research Hospital, where treatment is expected to cause a severely weakened immune system lasting more than 7 days
  • People expected to continue receiving care at St. Jude for at least 56 days after joining the trial
  • Female participants aged 9 or older who have a documented negative pregnancy test before receiving the study drug

Who may not be able to join:

  • People with a known allergy to vancomycin, dalbavancin, teicoplanin, levofloxacin, or ciprofloxacin (note: a mild infusion reaction to vancomycin that is not a severe allergic reaction does not count)
  • People who have had, or currently have, an infection or bacteria in their body that is resistant to vancomycin and also resistant to ciprofloxacin or levofloxacin
  • People who have been diagnosed with long QT syndrome (a heart rhythm condition)
  • People whose overall condition the trial doctor considers too high-risk for participation
  • People who currently have a suspected or confirmed active bacterial infection
  • People who, in the trial doctor's opinion, are unlikely to be able to complete what the trial requires
  • People whose expected survival is less than 28 days
  • People with certain liver test results that are significantly above the normal range for their age (confirm with trial site)
  • People with significantly reduced kidney function, based on a specific kidney filtration rate measurement (confirm with trial site)
  • People who have any other medical reason that prevents them from safely receiving the antibiotic medications used in this trial
  • People who are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Joshua Wolf, MBBS, St. Jude Children's Research Hospital

Phone: 8662785833

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
St. Jude Children's Research Hospital
Registry
ClinicalTrials.gov
Start date
22 May 2025
Est. completion
1 September 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Bacterial bloodstream infection

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov