Phase 2 Brain Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People diagnosed with a high-grade brain tumour called WHO Grade IV glioma, as defined by a specific Chinese cancer treatment guideline.
• People whose tumour has come back (recurred) after surgery, confirmed by a brain MRI scan.
• People who have at least one tumour that can be measured on a brain scan, according to a standard set of assessment criteria.
• People aged 18 to 70 years old (any gender).
• People whose steroid medication (dexamethasone), if taken for brain swelling caused by the tumour, has been at a stable low dose (under 6 mg per day) in the 7 days before joining the trial (confirm with trial site for specific dosing rules).
• People with a physical functioning score showing they are able to carry out at least limited self-care — a Karnofsky score of 40 or above, or a WHO performance score of 3 or below.
• People whose blood counts, liver function, and kidney function fall within acceptable ranges on tests taken within 14 days before treatment (confirm with trial site for specific values).
• People who are able to receive electroacupuncture treatment and are willing to attend consistently.
• People who are fully conscious, able to feel and identify pain, and can communicate at a basic level.
• People who have read and signed the informed consent form and are willing to take part voluntarily.

Who may not be able to join:

• People experiencing seizures that cannot be controlled.
• People who are currently enrolled in another clinical trial, or who finished another clinical trial less than one month ago.
• People who have previously received treatment with paclitaxel or similar drugs.
• People who have a severe allergic reaction to paclitaxel or similar substances.
• People who are pregnant or breastfeeding.
• People with conditions that affect thinking or memory, such as congenital dementia, or people with alcohol dependence, drug addiction, or misuse of mind-altering substances.
• People who have a skin infection at the location where acupuncture needles would be placed.
• People who have metal objects inside their body (such as implants or fragments).
• People who are unable to have a contrast-enhanced brain MRI scan.
• People with other serious medical conditions, mental health disorders, or abnormal test results that the trial doctor believes could increase health risks or affect the trial results.
• People who are currently receiving other cancer treatments at the same time, such as chemotherapy, radiotherapy, targeted therapy, or immunotherapy.

Important: Always verify eligibility with the trial site directly before applying.