Phase 2 Head and Neck Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have previously been diagnosed with a confirmed (biopsy-proven) squamous cell carcinoma (a type of cancer) of the voice box (larynx) or the area around it (hypopharynx), at stage II through to stage IV
- People who have previously been treated with radiation therapy, with or without chemotherapy
- People who are experiencing a return of their cancer in the same area, damage to tissue caused by radiation, or a voice box that is no longer working properly
- People aged 18 years or older
- People who are able to understand and sign a consent form agreeing to take part in the trial
Who may not be able to join:
- People who have an allergy to iodine or shellfish
- People for whom surgery under general anaesthetic is not considered safe
- People whose surgery is expected to involve removal of a larger area beyond the voice box (such as parts of the throat or oesophagus) requiring tissue from another part of the body to reconstruct the throat lining — though this may only be determined at the time of surgery (confirm with trial site)
- People who are pregnant or currently breastfeeding
- People who are currently living in prison
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Matthew E Spector, MD, University of Pittsburgh/UPMC
Phone: 412-647-2100
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence of PCF, within one month post total laryngectomy (TL)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.