Glaucoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years old or older and have been diagnosed with open-angle glaucoma (a type of glaucoma where the drainage angle in the eye is open) or high eye pressure, and your doctor considers you a suitable candidate for a standard laser eye treatment called SLT
• You have mild to moderate open-angle glaucoma (either the most common type, or a type caused by a build-up of a flaky material in the eye), based on results from a vision/eye pressure test
• You have high eye pressure with open drainage angles that your doctor feels needs treatment to lower
• Your eye pressure is between 22 and 35 mmHg (a unit used to measure eye pressure), measured after stopping any eye-pressure-lowering medications
• A specific part of your eye structure (the scleral spur) is fully visible all the way around during an eye examination
• The white area around the edge of your coloured eye (peri-limbal sclera) can be seen all the way around when your eyelid is gently lifted
• You are willing and able to take part in the study for about 60 days, follow all study procedures, and attend all scheduled appointments
• You are able to understand and sign a consent form agreeing to take part

Who may not be able to join:

• You have any condition that would make the standard SLT laser treatment unsafe for you (confirm with trial site)
• You have a type of glaucoma where the drainage angle is closed (angle closure glaucoma)
• You have a type of glaucoma that was present from birth or developed during childhood
• You have a secondary type of glaucoma, including a type caused by pigment in the eye (pigmentary glaucoma)
• You are unable to complete a reliable vision/visual field test (for example, if your results show too many errors or inconsistencies)
• You have abnormal tissue attachments inside the drainage angle of the eye being studied
• Your vision field test results show certain patterns of significant vision loss, including a vision loss score worse than -12dB, large areas of reduced vision, or loss of vision in the central area of your sight (confirm with trial site for the specific measurements)
• The ratio of the central hollow area to the total size of your optic nerve (the nerve connecting your eye to your brain) is greater than 0.8, indicating significant nerve damage
• You need more than two types of eye-pressure-lowering medications (a combination drop counts as two medications)
• You have previously had any surgery or laser treatment for glaucoma in the eye being studied, including a previous SLT laser treatment
• You have previously had laser or surgical treatment to correct your vision (such as LASIK)
• You had complicated cataract surgery within the last 6 months
• You have a cataract (clouding of the lens in the eye) that significantly affects your vision, in your doctor's opinion
• You have any other significant eye disease in either eye, as decided by the study doctor
• You have a significant lazy eye (amblyopia) in either eye
• You have heavy pigmentation, bleeding, or certain growths (such as a pinguecula or pterygium) on the white of your eye near the coloured area
• You are pregnant or may become pregnant during the study
• Your doctor thinks you may need other eye surgery within the next 12 months (other than for reducing eye pressure)
• You are currently using steroid medications in any form, including eye drops, nasal sprays, inhalers, or tablets
• You have an uncontrolled health condition that might prevent you from attending follow-up visits
• You are currently taking part in another clinical study
• You are considered a vulnerable person, including (but not limited to) those with intellectual disabilities, mental illness, prisoners, people who are terminally ill, or people with a weakened immune system
• You are unable to read and understand the consent form
• You are unable to read and understand English

Important: Always verify eligibility with the trial site directly before applying.