OCD Trial, Recruiting NCT06834217 Sponsor: Yale University Condition: OCD
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OCD Trial, Recruiting

NCT06834217
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You speak English fluently
  • You are able to give your agreement to participate in writing and verbally
  • You have been diagnosed with OCD (Obsessive-Compulsive Disorder) through a formal clinical interview
  • You are currently experiencing significant OCD symptoms
  • You have had OCD symptoms for at least 1 year
  • Your OCD is your main or one of your main mental health concerns (not secondary to another condition)
  • You have been on a stable mental health treatment plan for at least 8 weeks, or you are not currently receiving any treatment for OCD
  • Your OCD symptoms score at least 18 on a specific OCD symptom rating scale called the DOCS (confirm with trial site)

Who may not be able to join:

  • You currently have a serious problem with substance use (such as drugs or alcohol)
  • You are currently having thoughts of suicide
  • You have a history of bipolar disorder or a psychotic disorder (such as schizophrenia)
  • You have significant developmental disabilities
  • You have ever lost consciousness for more than 10 minutes
  • You have a history of traumatic brain injury
  • You have a major neurological disease (such as epilepsy or Parkinson's disease) (confirm with trial site)
  • You have a positive pregnancy test
  • You have a medical reason why you cannot have brain stimulation or an MRI scan (confirm with trial site)
  • You have started a new psychological therapy (such as talking therapy) within the past 8 weeks
  • You take a daily anti-anxiety medication such as a benzodiazepine (for example, Valium or Xanax)
  • (For healthy volunteers without OCD only) You currently meet the criteria for any mental health disorder, or you are taking any psychiatric medications

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: (203) 974-7523

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
12 September 2025
Est. completion
1 April 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Blood oxygen level-dependent (BOLD) response to create functional brain activation maps; Skin conductance response (SCR) will be measured by collecting electrodermal activity data from the left hand; Threat expectancies will be measured by asking participants to rate the probability of receiving a shock using a 0-100 scale with zero equal to 0% chance and 100 equal to 100% chance; higher values are indicative of worse anxious reactivity; Functional brain connectivity will be measured blood oxygen level dependent (BOLD) response

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov