Head and Neck Cancer Trial, Recruiting NCT06837480 Sponsor: Abramson Cancer Center at Penn Medicine Condition: Head and Neck Cancer
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Head and Neck Cancer Trial, Recruiting

NCT06837480
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are over 18 years old
  • People who have had head and neck cancer confirmed by a biopsy
  • People who have no signs of cancer at the time of joining the study, between 12 and 60 months after finishing cancer treatment
  • People who have had lymphedema (swelling caused by a build-up of lymph fluid) for at least 6 months
  • People who have swelling in at least 2 areas on the outside of the body (such as the face, neck, or nearby areas)
  • People who have at least 1 area of swelling rated as moderate severity using a specific assessment tool called the HN-LEF Assessment Criteria
  • People whose lymphedema has not fully responded to previous treatment, has gotten worse after treatment, has come back due to difficulty managing it at home, or where treatment could not be completed due to practical barriers
  • People who are able to understand English well enough to fill in questionnaires and to give informed consent to participate

Who may not be able to join:

  • Women of childbearing age or who could become pregnant
  • People who currently have an acute skin infection (cellulitis) in the head and neck area
  • People who have chronic inflammatory diseases
  • People who have a blood clot in a vein (venous thrombosis)
  • People who have a narrowing of the carotid artery (a major blood vessel in the neck)
  • People who need to regularly take water tablets (diuretics) or steroid medications (corticosteroids)
  • People who are currently receiving active lymphedema therapy or physical therapy, including treatments such as hyperbaric oxygen therapy or pentoxifylline (trental)
  • People who have a skin rash, ulcer, or open wound in the area where treatment would be given
  • People who have allergic skin conditions or other widespread skin diseases

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 2155732393

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Abramson Cancer Center at Penn Medicine
Registry
ClinicalTrials.gov
Start date
15 January 2026
Est. completion
30 August 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Total Severity of External Lymphedema

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov