Chronic Kidney Disease Trial, Recruiting NCT06841692 Sponsor: Erasmus Medical Center Condition: Chronic Kidney Disease
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Chronic Kidney Disease Trial, Recruiting

NCT06841692
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with chronic kidney disease at stage G3, meaning their kidney filtration rate (a measure of how well the kidneys clean the blood) was between 30 and 59 units at their last clinic visit
  • Healthy people whose kidney filtration rate is within the normal expected range for their age (a small, gradual decline in kidney function is considered normal from age 40 onwards)

Who may not be able to join:

  • People who have a known intolerance or allergy to water pills (diuretics)
  • People currently receiving chemotherapy for cancer
  • People who have received a kidney transplant
  • People currently taking a type of medication called calcineurin inhibitors
  • People whose life expectancy is less than 12 months
  • People currently receiving treatment to suppress the immune system for a kidney condition called glomerulonephritis
  • People who are unable to understand or follow instructions from the research team
  • People whose blood potassium level is too low or too high at the time of joining the trial
  • People whose blood sodium level is too low or too high at the time of joining the trial
  • People whose kidney disease is caused by an inherited condition affecting the kidney tubes (tubulopathy)
  • People whose kidney disease is caused by a condition called autosomal dominant polycystic kidney disease or tubulointerstitial kidney disease
  • People with significant heart failure classified as a severe level (New York Heart Association class III or IV)
  • People with very high blood pressure that has not responded to treatment (systolic reading above 180 mmHg at the time of joining)
  • People currently taking certain medications that affect how the kidneys process substances, including probenecid, pravastatin, cimetidine, cephalosporins, or acetazolamide
  • People with active hepatitis noted at their last clinic visit
  • People with advanced liver scarring (cirrhosis rated as Child-Pugh B or C)
  • People currently misusing drugs or alcohol
  • People who are unable to stop taking certain medications that interfere with the trial testing for a 28-day period beforehand
  • Women who are pregnant, breastfeeding, or planning to become pregnant before the test day

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ewout J. Hoorn, MD, PhD, Erasmus Medical Center

Phone: +31 6 39022349

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Erasmus Medical Center
Registry
ClinicalTrials.gov
Start date
1 April 2025
Est. completion
31 October 2029

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Progression of Chronic Kidney Disease

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov