Endometriosis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

All participants must meet these basic requirements:

• You must be willing to give your informed consent and sign a consent form
• You must be covered by a health insurance plan

Group 1 – People with adenomyosis (a condition affecting the uterus):

• You are female, aged between 28 and 57 years old
• You have not yet reached menopause
• Your doctor has recommended a full hysterectomy (removal of the uterus, keeping the ovaries) for a non-cancer reason
• You have been diagnosed with adenomyosis

Group 2 – People without adenomyosis but with another uterine condition:

• You are female, aged between 28 and 57 years old
• You have not yet reached menopause
• Your doctor has recommended a full hysterectomy (removal of the uterus, keeping the ovaries) for a non-cancer reason
• You have a functional uterine condition other than adenomyosis

Group 3 – Control group (people attending a fertility clinic):

• You are female, aged between 18 and 57 years old
• You have no symptoms such as heavy/irregular bleeding or pelvic pain
• You are being seen at the fertility clinic at Nîmes University Hospital for male-factor or unexplained infertility
• You are due to have an internal ultrasound (a scan using a small probe placed inside the vagina) as part of your fertility care
• Your uterus appears normal on that ultrasound

Who may not be able to join:

All groups:

• You have a history of an autoinflammatory or autoimmune disease (where the immune system attacks the body)
• You have a history of allergies, eczema, or asthma
• You have a history of sleep apnea (a condition where breathing stops briefly during sleep)
• You have chronic or acute kidney failure
• You have liver failure
• You have a current or past history of cancer or active tumour
• You have taken anti-inflammatory painkillers (such as ibuprofen), steroids, or aspirin in the 15 days before a specific measurement is taken in this trial
• You are currently using combined hormonal contraception (such as the combined pill or a hormonal patch)

Groups 1 and 2 only (adenomyosis groups):

• You are unable to have an MRI scan for medical reasons

Group 3 only (control group):

• You do not wish to have the internal ultrasound
• An ovarian cyst has been found on your scan or imaging (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.