Leukaemia Trial, Recruiting NCT06866873 Sponsor: Hong Kong Children's Hospital Condition: Leukaemia
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Leukaemia Trial, Recruiting

NCT06866873
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have acute lymphoblastic leukemia (ALL) or lymphoma that has come back or stopped responding to treatment, and you have already tried at least two different treatments that did not work well enough.
  • Your cancer has tested positive for a protein called CD19, based on a recent tissue or blood sample.
  • You are between 1 and 17 years old.
  • You are well enough to carry out some daily activities, as measured by a standard health scoring tool appropriate for your age (confirm with trial site).
  • Your liver, kidneys, and blood cell counts are within acceptable ranges based on recent lab tests (confirm with trial site).
  • It has been at least 2 weeks (or a short enough time based on the last treatment used) since your last cancer treatment, before the blood collection procedure begins.
  • A parent or legal guardian is able and willing to read and sign a consent form agreeing to take part.

Who may not be able to join:

  • You have had a stem cell transplant using your own cells within the last 6 weeks before the planned treatment.
  • You have previously received CAR-T cell therapy outside of this trial.
  • Your cancer has spread to the brain or the fluid surrounding the brain and spinal cord.
  • You have another active cancer (other than certain minor skin cancers or very early-stage cancers that are not spreading).
  • You have an active HIV infection.
  • You have another serious illness that is not under control, such as a serious infection, heart problems, breathing problems, or significant mental health conditions that could affect your ability to take part.
  • You are pregnant or breastfeeding.
  • There is evidence of a specific type of bone marrow disorder called myelodysplasia, found on a bone marrow test taken before starting this trial.
  • You have an active hepatitis B or hepatitis C infection, shown through a blood test.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Pamela Lee, MD, The University of Hong Kong

Phone: 852-35136049

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Hong Kong Children's Hospital
Registry
ClinicalTrials.gov
Start date
1 May 2024
Est. completion
31 December 2037

Where this trial is recruiting

Hong Kong

Primary endpoints

Complete response rate (CRR) for ALL and Overall response rate (ORR) for lymphoma; Incidence and severity of adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov