Endometrial Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 to 43 years old
- People who have fibroids (benign uterine growths) causing symptoms such as heavy bleeding, pain, or difficulty getting pregnant
- People whose fibroids are suitable for keyhole (laparoscopic) surgery — meaning the largest fibroid is 10cm or smaller, or there are 4 or fewer fibroids
- People whose fibroids require open abdominal surgery (laparotomy) — meaning the largest fibroid is bigger than 10cm, or there are more than 4 fibroids
- People for whom a specific technique to temporarily reduce blood flow to the uterus during surgery (called OTAU) is considered possible by the surgical team
- People who can speak and understand French
- People who are enrolled in the French social security system
Who may not be able to join:
- People who have previously had major uterine surgery or a fibroid removal operation (not including fibroid removal performed through a camera inserted via the vagina)
- People with a known allergy to misoprostol (a medication) or lactose
- People with a known sensitivity to misoprostol, other similar medications (prostaglandins), or any ingredients in those products
- People currently taking aspirin or blood-thinning (anticoagulant) medications
- People with conditions that affect how their blood clots
- People who are malnourished
- People with liver or kidney problems
- People who are pregnant, may have a pregnancy outside the womb (ectopic pregnancy), or are breastfeeding
- People under 18 years of age
- People under legal guardianship, curatorship, court protection orders, or who are currently detained (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Anne-Sophie GREMEAU, University Hospital, Clermont-Ferrand
Phone: +33473754963
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Evaluation of intraoperative blood loss (in milliliters) during myomectomies with OTAU after administration of misoprostol 400μg PO (experimental group) versus placebo (control group) regardless of type of surgery.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.