Phase 4 Myasthenia Gravis Trial, Recruiting NCT06909214 Sponsor: argenx Condition: Myasthenia Gravis
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Phase 4 Myasthenia Gravis Trial, Recruiting

NCT06909214
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older at the time of signing the consent form
  • You have been diagnosed with generalized Myasthenia Gravis (gMG) at a moderate to severe level (classified as MGFA class II, III, or IV)
  • Your blood tests show a specific antibody linked to Myasthenia Gravis (called AChR antibody)
  • You have either never been treated for gMG, or you have only taken a specific type of medication called an acetylcholinesterase inhibitor (a drug that helps muscles respond to nerve signals)
  • Your generalized Myasthenia Gravis symptoms started within the last 12 months before your screening appointment (or your eye-related MG symptoms started within the last 24 months)
  • Your daily life is significantly affected by MG symptoms, as measured by a standard scoring tool (a score of 5 or higher on the MG-ADL scale)

Who may not be able to join:

  • Your Myasthenia Gravis is classified at the mildest level (MGFA class I, affecting only the eyes) or the most severe level (MGFA class V, requiring a breathing machine)
  • You have previously had surgery to remove your thymus gland, unless it was removed to treat a non-cancerous thymus tumor before your MG diagnosis
  • You have previously used or are currently using steroid medications or other immune-suppressing drugs to treat your Myasthenia Gravis

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Phone: 857-350-4834

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
argenx
Registry
ClinicalTrials.gov
Start date
17 April 2025
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of participants who achieve MSE of MG at any time within the first 16 weeks of treatment with efgartigimod PH20 SC

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov