Phase 2 Chronic Kidney Disease Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are an adult with kidney failure who is treated with peritoneal dialysis (a type of home dialysis that uses fluid in the abdomen) and have been on a stable dialysis prescription using sugar-based dialysis fluid for at least 3 months.
• Your kidneys have been tested and shown to absorb fluid at a "high" or "high-average" rate, as measured by a specific test called a PET test (confirm with trial site).

Who may not be able to join:

• You have previously had a condition called euglycemic ketoacidosis (a serious chemical imbalance in the blood) (confirm with trial site).
• You have had an allergic reaction to a medication called canagliflozin.
• You currently have an active infection in your abdomen from dialysis, or an infection along your dialysis tube under the skin.
• You are expected to receive a kidney transplant within the next 6 months.
• You have severe liver disease (specifically a serious stage called Child-Pugh class C).
• You have repeated serious infections in your genital area or urinary tract.
• You are currently taking certain medications (digoxin, phenobarbital, phenytoin, rifampin, or ritonavir) that cannot be safely stopped during the trial.
• You are pregnant or currently breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.