Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older (or the legal age of consent in the country where the study takes place) at the time of signing the consent form.
• People who have at least one tumour that can be measured using standard imaging criteria (known as RECIST 1.1).
• People whose tumour has tested positive for a specific genetic change called homozygous MTAP-deletion, confirmed through a certified laboratory test.
• People who are relatively well and able to carry out daily activities, as measured by a standard health scale called ECOG — specifically, those rated 0 (fully active) or 1 (restricted in strenuous activity but able to do light work).

Who may not be able to join:

• People who have had a different type of cancer in the past 2 years, with some exceptions — such as certain minor skin cancers, early-stage cervical changes, superficial bladder tumours, localised prostate cancer, or other cancers that the treating doctor considers cured or not immediately life-threatening.
• People whose heart's electrical activity shows a prolonged interval (called QTc greater than 450 ms) on a heart tracing test — though people with a permanent pacemaker may still be considered, based on the treating doctor's assessment.
• People with a history of significant heart failure (Class II or higher on a standard medical scale), a heart attack within the past 6 months, or serious heart rhythm problems requiring treatment — with the exception of well-controlled atrial fibrillation managed only with digoxin or beta blockers.
• People who have had unstable chest pain (unstable angina) within the 4 weeks before starting the study treatment.

Important: Always verify eligibility with the trial site directly before applying.