Phase 1 Interstitial Lung Disease Trial, Recruiting NCT06919380 Sponsor: Li Shiyue Condition: Interstitial Lung Disease
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Phase 1 Interstitial Lung Disease Trial, Recruiting

NCT06919380
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with a specific type of muscle and skin disease called dermatomyositis, confirmed by a positive blood test for the anti-MDA5 antibody, according to 2023 Chinese expert guidelines
  • You also have a rapidly worsening type of lung scarring/inflammation (known as rapidly progressive interstitial lung disease) that meets specific diagnostic criteria

Who may not be able to join:

  • You are pregnant, breastfeeding, planning to become pregnant during the study, or are a man unwilling to use contraception throughout the trial
  • You have had a severe allergic reaction to the main ingredients in the trial medication
  • You currently have a severe lung infection, a collapsed lung (pneumothorax), or a large build-up of fluid around the lungs
  • You currently have a blood clot in the lungs (pulmonary embolism)
  • You are currently on a breathing machine connected through a tube in your throat (mechanical ventilation)
  • You are currently receiving life-support treatments such as ECMO, CRRT, PMX-DHP, or plasma exchange (confirm with trial site)
  • You currently have severe heart failure, or serious liver or kidney problems
  • You are expected to need a lung transplant in the near future
  • You currently have lung cancer, or lung nodules that may be early-stage lung cancer
  • You have a condition where your immune system does not work properly from birth (primary immunodeficiency)
  • You currently have an active infection such as HIV or active tuberculosis, and the research team considers this a concern
  • You have taken part in another clinical trial and received a different trial medication within the last 28 days, which the research team thinks could affect the results
  • The research team has any other concern that participating would not be in your best interest, such as concerns about your ability to follow the study requirements

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 020-81567301

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Li Shiyue
Registry
ClinicalTrials.gov
Start date
15 April 2025
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Three-Month Mortality Rate and Safety of Nebulized MSC-exos P1

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov