Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults (men and women) with a BMI of 25 or above but below 40 (meaning they are overweight or moderately obese)
• People whose health profile matches one of the specific metabolic types being studied in this trial (determined by a classification process)
• People whose weight has been stable (within about 3 kg) for at least the past 3 months

Who may not be able to join:

• People who have been diagnosed with, or are showing early signs of, type 1 or type 2 diabetes, based on blood sugar or related test results
• People with kidney or liver problems (either previously diagnosed or found through blood tests)
• People with digestive or gut diseases, or who have had abdominal surgery (though minor surgeries like appendix or gallbladder removal are generally allowed)
• People with food allergies, food intolerances (including gluten or lactose intolerance), or eating disorders that could interfere with the study
• People with heart disease or cancer (minor non-invasive skin cancer may be allowed)
• People with high blood pressure above certain levels, whether or not they are on medication for it
• People with conditions that affect how the body processes sugar or fats (confirm with trial site)
• People with a serious illness where life expectancy may be less than 5 years
• People with major mental health conditions
• People taking medication for thyroid disease (though people with well-managed underactive thyroid may be allowed)
• People with other physical or mental health conditions that could affect the study results
• People taking certain medications known to affect blood sugar or fat metabolism, including some diabetes medications, certain cholesterol-lowering drugs, or regular use of anti-inflammatory painkillers (confirm with trial site for your specific medications)
• People taking certain blood-thinning medications (other than low-dose aspirin)
• People taking antidepressants, unless they have been on a stable dose for at least 3 months before and throughout the study
• People taking statins (cholesterol medication), unless they have been on a stable dose for at least 3 months before and throughout the study
• People who have been on long-term steroid treatment (more than 7 days in a row)
• People who have taken antibiotics within the past 3 months
• People who exercise at a moderate-to-vigorous level for more than 4 hours per week
• People following a special or restricted diet (such as vegetarian, vegan, Atkins, or similar) that would conflict with the study diet
• People who are planning to lose or gain more than 5% of their body weight during the study
• People who drink more than 14 units of alcohol per week, or who use recreational drugs (including cannabis)
• People who are not willing to limit alcohol to no more than 7 drinks per week during the study
• People who smoke regularly, including use of e-cigarettes or vapes
• People who regularly take strong vitamin supplements or dietary supplements (such as pro- or prebiotics) that could affect the study results
• Women who are pregnant, breastfeeding, or planning to become pregnant
• People who are unable or unwilling to follow the study diet
• People who have donated blood in the last 3 months
• People who have taken part in another similar study in the last 3 months
• People who are unable to understand the study information or communicate with the study team
• People who are unwilling to be randomly assigned to a study group or to sign a consent form
• People who are unwilling to allow their data to be stored for 15 years
• People considered unsuitable for any other reason, as decided by the study doctor or lead researcher

Important: Always verify eligibility with the trial site directly before applying.