Migraine Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people with Visual Snow Syndrome (VSS):

• People aged between 18 and 60 years old
• People with good vision (20/25 or better in each eye), either naturally or with glasses — MRI-compatible glasses will be provided if needed
• People who are able to follow study instructions
• People who have been diagnosed with VSS by a specialist, or who experience flickering/static dots across their vision lasting more than 3 months plus at least 2 of these symptoms: seeing images that linger after looking away, visual effects from within the eye itself, trails behind moving objects, sensitivity to light, or difficulty seeing in the dark
• People who live in Minnesota within 2 hours of the study site

For people without Visual Snow Syndrome (comparison group):

• People aged between 18 and 60 years old
• People with good vision (20/25 or better in each eye), either naturally or with glasses — MRI-compatible glasses will be provided if needed
• People who are able to follow study instructions
• People who live in Minnesota within 2 hours of the study site

Who may not be able to join:

For people with Visual Snow Syndrome (VSS):

• People who are not fluent in English or another language for which translation services are available
• People who have a diagnosed or self-reported intellectual disability
• People who are currently dependent on substances (other than nicotine), or who experienced drug dependence with tolerance or withdrawal symptoms in the past 12 months
• People who have used hallucinogenic substances in the past 12 months, or within the 12 months before their VSS symptoms began
• People with a severe disease affecting the brain or nervous system
• People who have had a head injury involving a skull fracture or loss of consciousness for more than 30 minutes
• People with a physical condition that would make it difficult or impossible to carry out or interpret the study assessments (for example, loss of part of the visual field)
• People under 18 or over 60 years of age
• For the MRI part of the study: people with metal in the body that has not been approved as safe by the imaging centre's safety committee; people who are pregnant; people with certain conditions that affect blood flow in the brain (confirm with trial site); people with claustrophobia; people unable to lie still for at least one hour; people weighing more than 440 lbs; and, for any CT scan component only, people who have had research-related radiation exposure in the past 12 months
• People with any vision problem other than VSS or a need for corrective lenses (for example, crossed eyes, lazy eye, or colour blindness)
• People currently experiencing a psychotic episode

For people without Visual Snow Syndrome (comparison group):

• People who are not fluent in English or another language for which translation services are available
• People who have a diagnosed or self-reported intellectual disability
• People who are currently dependent on substances (other than nicotine), or who experienced drug dependence with tolerance or withdrawal symptoms in the past 12 months
• People who have used hallucinogenic substances in the past 12 months
• People with a severe disease affecting the brain or nervous system
• People who have had a head injury involving a skull fracture or loss of consciousness for more than 30 minutes
• People with a physical condition that would make it difficult or impossible to carry out or interpret the study assessments (for example, loss of part of the visual field)
• People under 18 or over 60 years of age
• For the MRI part of the study: people with metal in the body that has not been approved as safe by the imaging centre's safety committee; people who are pregnant; people with certain conditions that affect blood flow in the brain (confirm with trial site); people with claustrophobia; people unable to lie still for at least one hour; people weighing more than 440 lbs; and, for any CT scan component only, people who have had research-related radiation exposure in the past 12 months
• People with any vision problem or need for corrective lenses (for example, crossed eyes, lazy eye, or colour blindness)
• People who have ever had VSS symptoms or a VSS diagnosis
• People currently experiencing a psychotic episode

Important: Always verify eligibility with the trial site directly before applying.