Phenylketonuria Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
For people with PKU (Phenylketonuria):
Who might be able to join this trial:
- You have taken part in the PICO Study, or meet the criteria listed below
- You were diagnosed with PKU through a newborn screening test
- You started a low-phenylalanine (Phe) diet within the first 30 days of life
- You are 18 years old or older
- You are willing and able to give written consent to take part
Who may not be able to join:
- You have not been following a low-phenylalanine diet in the 6 months before the study
- Your phenylalanine blood levels were too high (above a certain level) in the 6 months before the study (confirm with trial site)
- You have another health condition that could significantly affect the study results (confirm with trial site)
- You are currently pregnant or breastfeeding
- You have metal particles in your head or brain, a pacemaker, deep brain stimulators, a cochlear implant, braces, or permanent retainers, as these interfere with MRI scans
For healthy volunteers (people without PKU):
Who might be able to join this trial:
- You are 18 years old or older
- You are willing and able to give written consent to take part
Who may not be able to join:
- You have a health condition that could significantly affect the study results (confirm with trial site)
- You are currently pregnant or breastfeeding
- You have difficulty following study instructions, for example due to not speaking German or French fluently, psychological disorders, or dementia
- You have metal particles in your head or brain, a pacemaker, deep brain stimulators, a cochlear implant, braces, or permanent retainers, as these interfere with MRI scans
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Regula Everts, Prof. Dr. phil., Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital and University of Bern, Switzerland
Phone: +41 31 63 2 84 97
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Brain Age Gap; Sustained Attention; Cognitive flexibility; Plasma concentration of Phe; Diffusion tensor imaging (DTI); Arterial Spin Labeling (ASL)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.