Brain Cancer Trial, Recruiting NCT06992973 Sponsor: Regina Elena Cancer Institute Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT06992973
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a single brain metastasis (cancer that has spread to the brain) that is 3 cm or larger in size, or a single brain metastasis between 2 cm and 3 cm that is causing symptoms and can be removed with surgery — with or without up to 3 additional small brain lesions that could be treated with targeted radiation
  • People who do not need urgent emergency brain surgery for severe neurological symptoms or dangerous pressure in the brain
  • People aged 18 or older
  • People whose general health and ability to carry out daily activities meets a certain minimum level, as measured by two standard medical scoring tools (ECOG scale score of 2 or below, and Karnofsky score of 60 or above) (confirm with trial site)
  • People whose doctors estimate they have a life expectancy of more than 3 months
  • People assessed as suitable for surgery based on a standard health scoring tool (ASA score of 3 or below), and who are able to have a brain MRI scan with and without contrast dye
  • People who are willing and able to read and sign an informed consent form

Who may not be able to join:

  • People for whom radiotherapy (radiation treatment) is not medically appropriate
  • People who are pregnant
  • People who are unable to follow study procedures or complete questionnaires

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Stefano Telera, Doctor, IRCCS National Cancer Institute

Phone: 0652662737

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Regina Elena Cancer Institute
Registry
ClinicalTrials.gov
Start date
26 September 2024
Est. completion
26 September 2029

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Local disease control

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov