Phase 2 Lupus Trial, Recruiting NCT07015983 Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Condition: Lupus
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Phase 2 Lupus Trial, Recruiting

NCT07015983
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with Systemic Lupus Erythematosus (SLE/Lupus) according to a specific set of medical guidelines called the EULAR/ACR 2019 criteria
  • People whose lupus has not responded well enough to steroid medications and at least 2 different immune-suppressing treatments, each taken for at least 3 months
  • People whose lupus is currently active at the time of joining the trial

Who may not be able to join:

  • People who have other illnesses, conditions, or are taking other treatments that could make it difficult for the trial team to measure the effects of the study treatment on lupus
  • People who have uncontrolled or serious heart or blood vessel problems, or significant brain or nervous system conditions
  • People who have a history of cancer or certain blood-related diseases, unless they have been free of that condition for 2 or more years (some exceptions may apply for certain minor, non-invasive cancers — confirm with trial site)
  • People who are pregnant, currently breastfeeding, or planning to become pregnant
  • People who have previously received CAR T cell therapy, genetically modified T cell therapy, a stem cell transplant, or an organ transplant
  • People who have received a live vaccine within 6 weeks before the chemotherapy preparation phase of the trial
  • People whose kidneys, liver, or other organs are not functioning at a level considered adequate for the trial (confirm with trial site for specific thresholds)
  • Additional criteria set out in the trial protocol may also apply (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb

Phone: 855-907-3286

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Registry
ClinicalTrials.gov
Start date
14 July 2025
Est. completion
17 May 2028

Where this trial is recruiting

🇦🇷 Argentina 🇦🇹 Austria 🇧🇪 Belgium 🇧🇷 Brazil 🇨🇦 Canada 🇩🇰 Denmark 🇫🇷 France 🇩🇪 Germany 🇮🇱 Israel 🇮🇹 Italy 🇯🇵 Japan 🇵🇱 Poland 🇵🇹 Portugal 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Proportion of participants achieving drug-free Definition of Remission in Systemic Lupus Erythematosus (DORIS) remission

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov