Obesity Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have given their informed consent to participate.
- Women aged between 18 and 60 years old (inclusive).
- People with obesity who meet the French health authority (HAS) criteria for bariatric (weight-loss) surgery — meaning a BMI of 35 or above with at least one related health condition, or a BMI above 40.
- People of European descent, with both parents identified by the patient as being of European origin (this pilot study limits participation to reduce variability in results).
- People who are using effective contraception, are abstinent, or have gone through menopause (as required for bariatric surgery eligibility).
- People who have at least two of the following signs of insulin resistance at the time of joining: high fasting blood sugar or type 2 diabetes; high blood pressure (130/85 mmHg or above); low "good" (HDL) cholesterol (below 50 mg/dL); or high triglycerides (fats in the blood, at 150 mg/dL or above).
- People covered by, or entitled to benefits under, a social security system.
- People having their bariatric surgery performed at Nantes University Hospital (CHU de Nantes).
Who may not be able to join:
- People whose diabetes medication has been changed in the past month.
- People who are currently using insulin or are planning to start insulin before their bariatric surgery.
- People whose cholesterol-lowering medication has been changed in the past three months.
- People currently taking steroid medications (such as cortisone-type drugs) that affect the whole body.
- People receiving antiviral treatment for HIV.
- People taking dietary supplements that affect fat metabolism, such as certain functional margarines (e.g., Proactive, Danacol), omega-3 or other polyunsaturated fatty acid supplements, or similar products identified by the research team.
- People with a condition where the pancreas does not produce enough digestive enzymes (exocrine pancreatic insufficiency).
- People who are pregnant or breastfeeding.
- People who have previously had an organ transplant.
- People who are in legal custody or under a legal protection arrangement such as guardianship or trusteeship.
- People with any other health condition that the research team considers could be harmed by participation or could affect the study.
- People already participating in another clinical trial (except non-interventional studies or research into surgical or post-operative techniques).
- People with Type 1 diabetes, a single-gene (monogenic) form of diabetes, or diabetes caused by another medical condition.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Marie De Montrichard, PH, Nantes University Hospital
Phone: +332 40 08 30 22
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Evaluate the effect of consuming oleic acid-rich sunflower oil versus conventional sunflower oil on cholesterol esterification within visceral white adipose tissue.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.