Phase 1 Interstitial Lung Disease Trial, Recruiting NCT07036029 Sponsor: Trevi Therapeutics Condition: Interstitial Lung Disease
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Phase 1 Interstitial Lung Disease Trial, Recruiting

NCT07036029
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a lung condition called IPF (idiopathic pulmonary fibrosis) by a lung specialist, using internationally recognised guidelines.
  • People whose blood oxygen level, measured by a fingertip sensor after sitting quietly for at least 5 minutes, is 92% or higher.
  • People whose lung capacity (measured by a breathing test called spirometry) is at least 40% of what would be expected for someone of their age, height, and sex.

Who may not be able to join:

  • People who have had a sudden worsening of their IPF in the last 3 months.
  • People who test positive for COVID-19 two days before entering the study facility.
  • People who have been diagnosed with COPD (chronic obstructive pulmonary disease), or whose breathing test results show a certain pattern associated with airway obstruction.
  • People who currently use oxygen overnight, at any amount or through any method (note: using oxygen during the day for short periods is allowed).
  • People who have been diagnosed with a sleep breathing disorder, such as sleep apnea.
  • People who have had a respiratory infection (in the nose, throat, or lungs) within the 8 weeks before entering the study facility.
  • People who have a history of aspiration pneumonitis (a type of lung inflammation caused by inhaling food, liquid, or stomach contents).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Chief Development Officer, Trevi Therapeutics

Phone: 203-654-3287

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Trevi Therapeutics
Registry
ClinicalTrials.gov
Start date
21 August 2025
Est. completion
30 June 2026

Where this trial is recruiting

🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Respiratory Function and Safety Assessed by Number of Participants With Increase in End Tidal Partial Pressure of Carbon Dioxide by Capnography (PetCO2) of at Least 10 Millimetres of Mercury (mmHg) From Baseline, or PetCO2>55 mmHg, for at Least 1 Minute; Respiratory Function and Safety as Assessed by Number of Participants With a Decrease in Blood Oxygen Saturation (SpO2) to <88% for at Least 1 Minute; Respiratory Function and Safety as Assessed by Number of Participants With a Decrease in Respiratory Rate (RR) to <6 Breaths per Minute; Safety and Tolerability as Assessed by Number of Particip...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov