Phase 2 Lung Cancer Trial, Recruiting NCT07038343 Sponsor: Avenzo Therapeutics, Inc. Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Recruiting

NCT07038343
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 75 years old who are generally able to carry out daily activities with little or no limitation, and who are expected to live for more than 3 months.
  • People with a confirmed diagnosis (through laboratory testing of tissue or cells) of a locally advanced or metastatic solid tumour of a specific type, as outlined in the trial protocol.
  • People whose cancer can be measured using standard imaging methods, as assessed by the trial investigator.
  • People willing to provide results from molecular (genetic) testing of their tumour, and to supply stored tumour samples or agree to a new biopsy if needed.

Who may not be able to join:

  • People with high blood pressure that is not well controlled.
  • People whose cancer has spread to the brain and is currently active or causing symptoms (those with treated, stable brain metastases that have not required steroid treatment for at least 4 weeks may still be considered).
  • People with a spread of cancer to the membranes surrounding the brain or spinal cord, even if it has been treated.
  • People with a history of lung disease caused by a previous drug treatment (a condition called drug-induced interstitial lung disease).
  • People with a history of any serious heart or cardiovascular condition.
  • People who have had a serious infection requiring intravenous (IV) medications within 2 weeks before the trial would start.
  • People who have previously received a solid organ transplant (such as a kidney, liver, or heart transplant).
  • There are additional criteria defined in the full trial protocol that may also affect eligibility (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: (858) 239-2944

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Avenzo Therapeutics, Inc.
Registry
ClinicalTrials.gov
Start date
4 June 2025
Est. completion
1 June 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Occurrence of Dose Limiting Toxicities (DLTs) during the first cycle (Phase 1); Determine the maximum tolerated dose (MTD) and/or preliminary recommended Phase 2 dose (RP2D) (Phase 1); Number of Participants with Treatment Emergent Adverse Events (TEAEs) and lab abnormalities (Phase 1); Objective Response Rate (ORR) (Phase 2)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov