Phase 1 Chronic Kidney Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have provided signed consent to participate
• People aged 18 years or older but under 65 years
• People with chronic kidney failure who are scheduled to receive a kidney transplant
• People with a body mass index (BMI) between 18 and 30 (a standard measure of body weight relative to height)
• People who weigh at least 50 kg (for males) or at least 45 kg (for females)
• People whose overall physical health status is classified by a doctor as ASA III or IV — meaning they have a serious ongoing medical condition (confirm with trial site)

Who may not be able to join:

• People who have liver disease, a psychiatric condition, or a neurological disorder
• People who have a blood clotting disorder
• People who have heart failure
• People who have respiratory (breathing) failure
• People who use sedatives or antidepressants on a long-term basis
• People who are pregnant or breastfeeding
• People who are unable to communicate or cooperate with trial requirements
• People who have taken part in another drug or medical device trial within the past 3 months
• People who test positive for hepatitis B
• People who test positive for hepatitis C
• People who test positive for HIV
• People who test positive for syphilis
• People who have taken certain medications that affect liver enzymes within the past 30 days (confirm with trial site for the specific list)
• People with a known allergic or sensitivity reaction to two or more substances
• People who have consumed more than 14 units of alcohol per week at any point in the 6 months prior to the trial
• People with a history of drug abuse within the past 3 months
• People who have had a major infection or serious physical injury within the past month
• People who have had gastrointestinal (digestive tract) surgery that could affect how the body absorbs medication within the past month
• People who have received a vaccine within the past month, or who plan to receive one during the study period
• People who have lost or donated more than 400 mL of blood within the past 3 months
• People who have received a blood transfusion within the past month
• People whose blood clotting test results fall outside acceptable ranges (confirm with trial site)
• People with a history of significant bleeding episodes within the past 3 months
• People who are currently taking blood-thinning (anticoagulant) medication
• People whom the trial investigator considers unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.