Chronic Kidney Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Cohort 1: Healthy Participants
Who might be able to join this trial:
- Adults between 18 and 75 years old
- People with normal kidney function
- People without heart failure
- People with a body mass index (BMI) between 25 and 30 (considered overweight but not obese)
Who may not be able to join:
- People with a long-term (chronic) illness
- People whose kidneys are not filtering blood well enough (confirm with trial site)
- People who are pregnant or breastfeeding
- People who have had a skin or allergic reaction to iodine-based products or contrast dyes (a type of liquid sometimes used in medical scans)
- People with low levels of red blood cells (confirm with trial site)
- People who have been acutely unwell or hospitalised in the past 3 months
- People who are unable to stop taking anti-inflammatory pain medications (such as ibuprofen or naproxen)
- People with certain serious conditions, including multiple myeloma, amyloidosis, a type of adrenal gland tumour (pheochromocytoma), sickle cell disease, brain tumours that have spread, advanced kidney disease, liver problems, a severe bloodstream infection, or an overactive thyroid
- People who currently use nicotine or recreational drugs, or who drink alcohol heavily on a regular basis
Cohort 2: Obese Participants without Heart Failure
Who might be able to join this trial:
- Adults between 18 and 75 years old
- People with adequate kidney function (confirm with trial site)
- People with a BMI greater than 35 (considered severely obese)
Who may not be able to join:
- People who have been diagnosed with heart failure
- People with a long-term (chronic) illness
- People whose kidneys are not filtering blood well enough (confirm with trial site)
- People who are pregnant or breastfeeding
- People who have had a skin or allergic reaction to iodine-based products or contrast dyes
- People with low levels of red blood cells (confirm with trial site)
- People who have been acutely unwell or hospitalised in the past 3 months
- People who are unable to stop taking anti-inflammatory pain medications (such as ibuprofen or naproxen)
- People with certain serious conditions, including multiple myeloma, amyloidosis, pheochromocytoma, sickle cell disease, brain tumours that have spread, advanced kidney disease, liver problems, a severe bloodstream infection, or an overactive thyroid
- People who currently use nicotine or recreational drugs, or who drink alcohol heavily on a regular basis
Cohort 3: Obese Participants with a Specific Type of Heart Failure (HFpEF)
Who might be able to join this trial:
- Adults between 18 and 75 years old
- People with adequate kidney function (confirm with trial site)
- People with a BMI greater than 35 (considered severely obese)
- People who have been diagnosed with a specific type of heart failure called HFpEF, confirmed by heart scan results and a clinical scoring tool (confirm with trial site)
Who may not be able to join:
- People whose heart failure symptoms are severe (classified as NYHA Class III or IV — meaning significant or severe limitations on physical activity)
- People who have difficulty emptying their bladder fully
- People with mobility difficulties
- People who have previously had dialysis or a kidney transplant
- People who have been acutely unwell or hospitalised in the past 3 months
- People with a history of cancer, chemotherapy, or radiation therapy
- People who are pregnant or breastfeeding
- People who have had a skin or allergic reaction to contrast dyes
- People with low levels of red blood cells (confirm with trial site)
- People with certain serious conditions, including multiple myeloma, amyloidosis, pheochromocytoma, sickle cell disease, brain tumours that have spread, advanced kidney disease, liver problems, a severe bloodstream infection, or an overactive thyroid
- People who are unable to stop taking anti-inflammatory pain medications (such as ibuprofen or naproxen)
- People who currently use nicotine or recreational drugs, or who drink alcohol heavily on a regular basis
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Marissa C Tio, MD, University of Mississippi Medical Center
Phone: 601-496-7834
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in measured GFR; Change in urine sodium excretion
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.