PTSD Trial, Recruiting NCT07055373 Sponsor: University of Calgary Condition: PTSD
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PTSD Trial, Recruiting

NCT07055373
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People whose symptoms started at least 3 months ago but less than 10 years ago
  • People whose whiplash injury has been classified as Grade I (neck pain only), Grade II (neck pain with reduced movement or tenderness), or Grade III (neck pain with signs of nerve involvement found during a physical examination)
  • People whose average neck pain over the past week has been rated at least 4 out of 10
  • People whose score on a neck disability questionnaire (the Neck Disability Index) is above 28%, which works out to more than 14 out of 50 points

Who may not be able to join:

  • People with a Grade IV whiplash injury, which involves fracture or dislocation of the spine
  • People currently experiencing concussion symptoms
  • People who have previously had a surgical procedure to cut the vagus nerve in the neck
  • People who have been diagnosed with a severely slow heart rate (severe bradycardia)
  • People who have a permanent metal or electronic device, or jewellery, located close to the front of the ear (the ear tragus)
  • People who have any active implanted device (such as a cochlear implant, brain shunt, or internal vagus nerve stimulator) or a non-active implant that could interact with the nervous system (such as metal implants)
  • People who have open wounds, rashes, swelling, redness, infection, or skin irritation, or any cancerous lesions, in the area where stimulation would be applied
  • People who are currently taking medications that affect the autonomic nervous system, such as beta blockers
  • People with certain other health conditions, including a neurological disorder (such as multiple sclerosis), an inflammatory condition (such as rheumatoid arthritis), a serious heart condition or heart attack within the last 5 years, a metabolic condition (such as diabetes), significant vision problems (such as cataracts or double vision), known or suspected serious spinal disease (such as cancer affecting the spine), pregnancy, or a history of spinal surgery or repeated treatment for spinal problems
  • People who had a diagnosed mental health condition — such as bipolar disorder, schizophrenia, anxiety, PTSD, or severe depression — before the motor vehicle accident that caused their whiplash
  • People who are unable to complete the study questionnaires

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ashley Smith, University of Calgary

Phone: 403-265-3838

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Calgary
Registry
ClinicalTrials.gov
Start date
21 January 2026
Est. completion
1 January 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Number of participants with treatment-related adverse events (AEs); recruitment rate; attendance rate; retention rate.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov