Chronic Kidney Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People between 40 and 70 years old
• Men, or women who have gone through menopause
• People who have been diagnosed with Stage 3 chronic kidney disease, meaning their kidneys are working at a reduced level (confirmed by a specific kidney function test result between 30–59 ml/min/1.73m²)
• People whose kidney function test result is 45 or above must also have a high level of a protein called albumin in their urine (above 300mg/g creatinine on a urine test)
• People who are willing to follow a controlled, set diet for the whole duration of the study
• People who are willing to collect stool samples at home during the study

Who may not be able to join:

• People whose blood sugar control test (HbA1c) showed a result above 7% in the last six months
• People who have been treated with metformin or insulin in the last three months
• People whose blood pressure has been recorded above 150/100 mmHg on at least two occasions in the past month
• People who have had a change in their heart or blood pressure medications in the last 30 days
• People with a history of significant bowel or digestive conditions, such as inflammatory bowel disease, uncontrolled irritable bowel syndrome, ongoing C. difficile infection, coeliac disease, diverticulitis, or stomach or duodenal ulcers
• People with a known HIV diagnosis
• People who have been hospitalised in the last two months
• People who have lost 5% or more of their body weight without trying over the past three months
• People who have had cancer or received cancer treatment in the past year (except for a type of minor skin cancer called basal cell carcinoma)
• People who have previously had weight-loss (bariatric) surgery, such as gastric bypass, sleeve gastrectomy, or gastric band
• People who have used immune-suppressing medications in the past six months, or who have taken a steroid called prednisone at a dose above 10mg per day for more than one week in the past three months (or an equivalent dose of a similar steroid)
• People who have taken antibiotics in the past three months (even one course), or two or more courses of antibiotics in the past six months
• People with a known food allergy that would make it difficult to follow the study's required diets
• People who have had high potassium levels in their blood (above 5.5 mmol/L) on at least two separate occasions
• People with other medical conditions or concerns that the trial investigators consider relevant (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.