Phase 3 Chronic Kidney Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- A parent or legal guardian (and the child, where appropriate for their age and understanding) must agree to take part by signing a consent form before the trial begins.
- Children and teenagers aged 2 to 17 years old at the time of the first screening visit.
- Has chronic kidney disease (long-term kidney damage) of any cause, with kidney function and protein levels in urine falling within specific ranges measured by a central lab at screening (confirm with trial site for exact values).
- Has been on a stable, maximum tolerated dose of standard kidney disease treatment for at least 30 days before screening, with no plans to change it during the main part of the trial — this typically includes a blood pressure/kidney-protecting medication such as an ACE inhibitor or ARB, and possibly an additional medication called a mineralocorticoid receptor antagonist if needed and stable.
- If taking daily medications to suppress the immune system for an underlying kidney condition, the dose must have been stable for a set period before screening and must stay stable throughout the main part of the trial.
- There are additional inclusion requirements not listed here (confirm with trial site).
Who may not be able to join:
- Has been diagnosed with type 1 or type 2 diabetes.
- Has had a serious complication called ketoacidosis within 8 weeks before the first visit or before being enrolled.
- Is currently on dialysis, has a working donor kidney (transplant), or is scheduled to receive a kidney transplant during the trial.
- Has been diagnosed with a bone disease related to metabolism that is not well controlled.
- Has a body weight that is considered too low for their age and height, based on standard growth charts (confirm with trial site for exact thresholds).
- Has a stomach or digestive condition that could affect how the trial medication is absorbed into the body.
- Has a current or recent urinary tract infection (UTI), including having been treated for one within 14 days before the first screening visit.
- Has severely high blood pressure that is not well controlled.
- There are additional reasons a person may not be able to join that are not listed here (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 1-800-243-0127
Australian sites
1800271035
1800271035
1800271035
1800271035
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
4 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
Change from Day 1 to the Week 24 visit in urine albumin-creatinine (UACR) [mg/g]; Change from Day 1 to the Week 24 visit in urine glucose [mmol/L]
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.