Phase 2 Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are able to give written consent and agree to follow the study schedule and requirements
• People aged 18 to 75 years at the time of signing the consent form
• People who have been confirmed through laboratory testing (tissue or cell samples) to have small cell lung cancer
• People with limited-stage disease (a specific stage range assessed through scans and procedures such as PET-CT, bronchoscopy, or biopsy) where the treating surgeon considers the tumour removable with the goal of no cancer cells left behind — this includes certain tumour sizes and lymph node involvement, but excludes tumours that have grown into surrounding structures such as the heart, windpipe, or spine, and excludes more than one lymph node station being affected (confirm with trial site)
• People who have not previously received any radiotherapy, chemotherapy, immunotherapy, surgery, or other systemic cancer treatments
• People with a performance status score of 0 or 1 on the ECOG scale, meaning they are fully active or have only minor limitations in physical activity (confirm with trial site)
• People whose life expectancy is greater than 3 months
• People whose blood counts and organ function are within an acceptable range within 30 days before joining, as required to safely receive platinum-based chemotherapy
• People without any medical reasons preventing them from receiving immunotherapy

Who may not be able to join:

• People whose tumour testing shows a different type of lung cancer called non-small cell lung cancer (NSCLC)
• People who have cancer that has spread to the brain, whether currently active or previously treated but now considered inactive
• People who have a history of, currently have, or show signs of interstitial lung disease (a group of conditions involving scarring or inflammation of the lungs), including pulmonary fibrosis or radiation-related lung inflammation
• People who have been taking steroid medications (corticosteroids) systemically within 14 days before the first study treatment
• People who have previously received radiotherapy, chemotherapy, immunotherapy, surgery, or other systemic cancer treatments
• People who have had any other active cancer within the 2 years before joining
• People who are pregnant, breastfeeding, or planning to become pregnant during the study
• People with serious or uncontrolled heart or blood vessel disease at the time of joining
• People who have or have had active autoimmune or inflammatory diseases
• People with a history of primary immune system deficiency disorders
• People with a current active infection
• People who have had active bleeding problems within 6 months before starting the study treatment, including vomiting blood, severe coughing up of blood, or blood in the stool
• People with wounds that are not healing, active stomach ulcers, or bone fractures
• People whom the trial doctor considers unsuitable for participation for any other reason

Important: Always verify eligibility with the trial site directly before applying.