Melanoma Trial, Recruiting NCT07112170 Sponsor: University Health Network, Toronto Condition: Melanoma
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Melanoma Trial, Recruiting

NCT07112170
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older
  • People whose general health and ability to carry out daily activities falls within a certain range (a medical score called ECOG 0–2 — confirm with trial site what this means for a specific situation)
  • People who are willing and able to give informed consent to take part
  • People who have metastatic melanoma (melanoma that has spread to other parts of the body) confirmed by scans and clinical assessment
  • People who have already received a first course of treatment, either immunotherapy or BRAF inhibitor therapy, for their melanoma
  • People who have no more than ten sites in the body (outside the brain) where the cancer is actively growing or progressing, counting both the original tumour and any spread sites
  • People who have had previous radiation therapy near or overlapping with the areas of progression may still be considered
  • People where all sites of progression can be safely treated with a targeted form of radiation therapy called SBRT or hypofractionated radiotherapy (confirm with trial site)

Who may not be able to join:

  • People with more than ten sites outside the brain where the cancer is actively progressing
  • People who are pregnant
  • People whose cancer has spread to the lining of the brain or spinal cord (a condition called leptomeningeal disease)
  • People with serious medical conditions that would make radiation therapy unsafe, such as ataxia-telangiectasia or scleroderma
  • People who have had previous radiation therapy so close to the affected areas that further radiation would risk exceeding safe limits for nearby healthy tissue
  • People with psychological, social, or geographical circumstances that may make it difficult to follow the trial requirements
  • People whom the trial investigator considers unsuitable for participation for any other medical reason

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 416-946-4501

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 July 2025
Est. completion
24 July 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Progression-Free Survival (PFS) assessed by radiological imaging using RECIST v1.1 criteria

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov