Phase 1 OCD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 65 years old (inclusive)
• You are willing and able to give your consent to take part and can attend the required study visits, as agreed by both the study psychiatrist and surgeon
• You have been diagnosed with Anorexia Nervosa along with OCD and/or Major Depressive Disorder, as defined by standard psychiatric guidelines
• Your condition has not responded to previous treatments, shown by at least one of the following: your illness has lasted more than 10 years with no more than 3 months of healthy weight recovery; you have had at least 3 attempts at specialist hospital-based treatment without lasting success; or you have needed emergency or involuntary refeeding at least twice over at least 2 years due to medical deterioration
• You are able to understand and agree to the study's terms and make your own medical decisions

Who may not be able to join:

• You have an unstable or serious heart condition, such as recent heart attack (within 6 months), certain heart failure, uncontrolled high blood pressure, or are on certain heart medications
• You have a metal implant or device in your body (such as a pacemaker) that is not safe for MRI scanning, or you cannot fit in an MRI machine
• Your blood tests show problems with bleeding or blood clotting, including a low platelet count or abnormal clotting levels
• You have had a stroke or bleeding in the brain within the last 6 months, or have a history of bleeding in the brain
• You have sleep apnea that is not being treated or controlled
• You are taking blood-thinning or anti-clotting medications (such as warfarin or aspirin) within one week before the procedure, or certain other medications that increase bleeding risk within one month before the procedure
• You are unable or unwilling to lie still on your back for a long period of time during the treatment
• You have taken part in another clinical trial in the last 30 days
• You are unable to communicate with the study team
• You have significant problems with memory or thinking
• You have a history of psychosis
• You have a known or newly discovered brain tumour
• You are currently pregnant or breastfeeding
• You have had a problem with alcohol or drug misuse in the last 6 months
• You have a medical condition affecting how your body processes food or digestion (such as diabetes)
• Your Body Mass Index (BMI) is below 13 (confirm with trial site if unsure how to calculate this)

Important: Always verify eligibility with the trial site directly before applying.