Phase 3 Leukaemia Trial, Recruiting NCT07132684 Sponsor: Institute of Hematology & Blood Diseases Hospital, China Condition: Leukaemia
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Phase 3 Leukaemia Trial, Recruiting

NCT07132684
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with Acute Myeloid Leukemia (AML) based on specific internationally recognised diagnostic guidelines (WHO 2022 or ICC criteria)
  • People aged between 55 and 75 years old
  • People who are reasonably active and able to carry out daily activities — assessed using a standard scale where a score of 0 means fully active and 2 means able to care for oneself but unable to do physical work
  • People whose liver is functioning well enough, based on blood test results showing liver-related values within acceptable ranges
  • People whose kidneys are functioning well enough, based on blood test results within acceptable ranges
  • People whose heart enzyme levels are within acceptable ranges on blood tests
  • People whose heart is pumping blood effectively, confirmed by a heart ultrasound (echocardiogram) showing a normal result
  • People who have given written agreement to participate (or whose legal representative has done so)

Who may not be able to join:

  • People whose AML involves a specific genetic change called PML-RARA fusion — a subtype known as Acute Promyelocytic Leukemia
  • People whose AML involves specific genetic changes called RUNX1-RUNX1T1 or CBFB-MYH11 fusions
  • People whose AML involves a specific genetic change called BCR-ABL fusion
  • People whose AML has come back after treatment or has not responded to previous chemotherapy (note: prior use of a drug called hydroxyurea is generally acceptable)
  • People who have another type of cancer that currently requires treatment
  • People with serious heart conditions, such as uncontrolled chest pain, a recent heart attack, severe irregular heartbeat, uncontrolled heart failure, or an abnormal heart pumping result
  • People with severe active infections, such as untreated tuberculosis or a serious fungal lung infection called pulmonary aspergillosis
  • People who the trial doctor considers unsuitable for other medical reasons (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Hui Wei, MD, Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Phone: 13132507161

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Registry
ClinicalTrials.gov
Start date
31 August 2025
Est. completion
30 August 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Overall Survival (OS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov