Phase 1 Bladder Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be willing and able to sign a consent form agreeing to take part in the trial.
• You must be 18 years of age or older and able to understand and agree to the consent process.
• You must have been diagnosed with a specific type of lung cancer (non-small cell lung cancer) or bladder cancer, confirmed by a laboratory test on tissue, and be a candidate for a type of immunotherapy treatment.
• A specific protein test (called PD-L1) must have already been done on your cancer tissue, or there must be enough tissue available to do this test.
• You must be reasonably active and able to care for yourself — this is measured by a standard scale where a score of 0, 1, or 2 is required (confirm with trial site).
• Your blood, kidney, and liver levels must be within an acceptable range, based on blood tests done within 28 days before joining the trial.
• If you are a woman who could become pregnant, you must have a negative pregnancy blood test within 24 hours before receiving the study scan drug.
• Women who cannot become pregnant may join if they have had a surgical procedure to prevent pregnancy or have been through menopause for at least 1 year.
• If you are a woman who could become pregnant, or a man whose partner could become pregnant, you must agree to use an appropriate form of contraception during the trial.

Who may not be able to join:

• You may not be eligible if you have recently been treated with certain immunotherapy drugs (anti-PD-L1 or anti-PD-L2 treatments) — at least 4 months must have passed since that treatment ended.
• You may not be eligible if you are still experiencing significant side effects from a previous cancer treatment that have not improved to a mild level.
• You may not be eligible if you have been taking increasing doses of steroid medications (such as dexamethasone) in the 7 days before starting the trial treatment — stable or low doses, as well as inhaled or skin-applied steroids, may be acceptable (confirm with trial site).
• You may not be eligible if you have had a serious allergic reaction to a similar type of drug (monoclonal antibody) in the past, or if you are known to be allergic to any ingredients in the study drugs.
• You may not be eligible if you have another serious medical condition or active infection that the trial doctor believes could make it unsafe for you to participate.
• You may not be eligible if you are pregnant, based on a test taken within 24 hours before the study scan.
• You may not be eligible if you are currently breastfeeding.
• You may not be eligible if you are unable to follow the requirements and schedule of the trial.

Important: Always verify eligibility with the trial site directly before applying.