Phase 1 Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are able to understand the trial procedures and possible side effects, and are willing to sign a written consent form
• Male participants aged 18 to 55 years old at the time of signing the consent form
• People with a body weight of at least 65 kg and a body mass index (BMI) between 24.0 and 35.0 (a measure of body weight relative to height)
• People whose weight has not changed by more than 5 kilograms in the past 3 months
• People who have been assessed by the trial doctors — through medical history, physical checks, vital signs, blood tests, and a heart tracing (ECG) — and determined to be suitable overweight or obese participants

Who may not be able to join:

• People who are known or suspected to be allergic to any ingredient in the trial drug or related products, or who have a history of multiple, severe, or serious allergic reactions to medicines or foods
• People with a chronic or serious medical history affecting the lungs, heart, digestive system, kidneys, blood, hormones, immune system, nerves, or mental health, or who currently have any of these conditions and are judged by the trial doctors to be unsuitable
• People with a history of high blood pressure, or whose blood pressure readings during screening are considered abnormal and clinically significant by the trial doctors
• People with a notable history of digestive or stomach problems (such as nausea, vomiting, heartburn, or diarrhoea), conditions that slow stomach emptying, any prior stomach or bowel surgery (except removal of intestinal polyps or the appendix), or who had acute diarrhoea in the 7 days before joining
• People who have taken part in a clinical trial of any medicine or medical device within the 3 months before dosing, or within 5 half-lives of that drug — whichever period is longer
• People who have donated blood or lost 400 mL or more of blood in the 3 months before dosing, or 200 mL or more in the month before dosing, or who received a blood transfusion within the 3 months before dosing
• People who test positive for Hepatitis B, Hepatitis C, HIV, or syphilis
• People with a history of drug abuse or illicit drug use, or who test positive on a urine drug screening test during the screening period
• People who drink heavily (averaging 14 or more units of alcohol per week in the 6 months before screening), smoke 5 or more cigarettes per day on average, are unable to stop smoking or drinking during the trial, or who test positive on a blood alcohol test (confirm with trial site for exact definitions)

Important: Always verify eligibility with the trial site directly before applying.