Phase 2 Brain Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have up to two large tumours that have spread to the brain
- People who have up to 10 brain metastases (tumours that have spread to the brain) in total at the time of enrolment — these may be previously untreated or may have grown back after earlier treatment
- People aged 18 or older
- People whose general health and ability to perform daily activities falls within a certain range, as assessed by a standard medical scoring tool called the ECOG scale (scores 0–2) (confirm with trial site)
- People whose doctors expect them to survive more than 3 months
- People whose doctors consider them suitable to receive either of the two types of radiation treatment used in this trial (GammaKnife and Linac-based)
- People who are able to pause their systemic cancer treatments (such as chemotherapy or immunotherapy) for at least 2 days before and after each radiation treatment session
Who may not be able to join:
- People who have already had the specific type of targeted brain radiation used in this trial (SRS) on the larger tumours being studied
- People who have previously had whole-brain radiation therapy, or who are planned to receive it at the same time as the trial treatment
- People who have, or have had, cancer spreading along the lining of the brain or spinal cord
- People whose cancer has spread into the fluid-filled spaces (ventricles) of the brain or a specific connecting structure in the brain called the corpus callosum
- People whose original (primary) cancer is small cell lung cancer, a blood cancer, or a germ cell cancer
- People who have an absolute medical reason why they cannot have an MRI scan
- People whose symptoms are too severe to undergo MRI scanning or the radiation treatments used in this trial
- People who are pregnant or breastfeeding
- People who are unable or unwilling to give informed consent or attend follow-up appointments after treatment
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 4164804974
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Cumulative incidence of late local complication (LLC)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.