PTSD Trial, Recruiting NCT07164105 Sponsor: Laureate Institute for Brain Research, Inc. Condition: PTSD
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PTSD Trial, Recruiting

NCT07164105
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You work in a frontline healthcare role, such as emergency medical services
  • You are between 18 and 65 years old
  • You have scored within a certain range on a standard PTSD questionnaire (PCL-5 score of 33 or above but below 65), or you have been assessed as having at least partial PTSD through a structured interview called the MINI
  • You are able to speak and understand English well enough to take part, as assessed during the screening process

Who may not be able to join:

  • You have a neurological disorder (a condition affecting the brain or nervous system)
  • You have been diagnosed with certain mental health conditions, including psychosis, an eating disorder, obsessive-compulsive disorder, bipolar disorder, major depression with psychosis, or a moderate to severe alcohol or drug use problem within the past year
  • You have current thoughts of suicide with a plan or intent, or you have made a suicide attempt in the last 3 months (confirm with trial site)
  • You have a history of severe traumatic brain injury or skull fractures
  • You have any condition or implant that makes it unsafe for you to have an MRI scan
  • You are pregnant (a urine pregnancy test will be done before each MRI scan)
  • You have recently changed the dose of a medication that could affect brain function — such as antidepressants, anti-anxiety medications, or mood stabilizers — within the last 6 weeks
  • You have vision or hearing problems that cannot be corrected with glasses, contacts, or hearing aids
  • You have a medical condition that is not currently stable or well-controlled
  • You have any structural abnormalities found in a specific area of your brain on your screening MRI scan
  • The trial team judges that you may not be able to follow the study procedures for any reason (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 918-340-4116

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Laureate Institute for Brain Research, Inc.
Registry
ClinicalTrials.gov
Start date
29 December 2025
Est. completion
1 August 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

LIFU target engagement; Behavioral changes

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov